Publications

The Center for Chemical Evolution brings together a diverse group of scientists with backgrounds from several disciplines of chemistry and chemical engineering. Our continued research efforts focus on exploring chemical evolution and the chemistry associated with the origins of life. We anticipate that discoveries made within the Center will significantly contribute to this field, as well as to the greater scientific community. Our recent peer-reviewed publications are listed below.

Raggi, L., Bada, J. L., & Lazcano, A. (2016). On the lack of evolutionary continuity between prebiotic peptides and extant enzymes. Physical Chemistry Chemical Physics.
http://dx.doi.org/ 10.1039/C6CP00793G

Cafferty, B. J., Musetti, C., Kim, K., Horowitz, E. D., Krishnamurthy, R., & Hud, N. V. (2016). Small molecule-mediated duplex formation of nucleic acids with ‘incompatible’ backbones. Chemical Communications, 52(31), 5436-5439.
http://dx.doi.org/ 10.1039/C6CC00779A

La Cruz, N. L., Qasim, D., Abbott-Lyon, H., Pirim, C., McKee, A. D., Orlando, T., ... & Pasek, M. A. (2016). The evolution of the surface of the mineral schreibersite in prebiotic chemistry. Physical Chemistry Chemical Physics.
http://dx.doi.org/10.1039/C6CP00836D

Cafferty, B. J., Fialho, D. M., Khanam, J., Krishnamurthy, R., & Hud, N. V. (2016). Spontaneous formation and base pairing of plausible prebiotic nucleotides in water. Nature Communications, 7.
http://dx.doi.org/10.1038/ncomms11328

Bernier, M. C., Alberici, R. M., Keelor, J. D., Dwivedi, P., Zambrzycki, S. C., Wallace, W. T., ... & Macatangay, A. (2016). Microplasma Ionization of Volatile Organics for Improving Air/Water Monitoring Systems On-Board the International Space Station. Journal of The American Society for Mass Spectrometry, 1-8.
http://dx.doi.org/10.1007/s13361-016-1388-y

Butch, C. J., Wang, J., Gu, J., Vindas, R., Crowe, J., Pollet, P., ... & Liotta, C. L. (2016). pH‐controlled reaction divergence of decarboxylation versus fragmentation in reactions of dihydroxyfumarate with glyoxylate and formaldehyde: parallels to biological pathways. Journal of Physical Organic Chemistry.
http://dx.doi.org/10.1002/poc.3542

Li, S., Mehta, A. K., Sidorov, A. N., Orlando, T. M., Jiang, Z., Anthony, N. R., & Lynn, D. G. (2016). Design of Asymmetric Peptide Bilayer Membranes. Journal of the American Chemical Society, 138(10), 3579-3586.
http://dx.doi.org/10.1021/jacs.6b00977  

Keelor, J. D., Farnsworth, P. B., Weber, A. L., Abbott-Lyon, H., & Fernández, F. M. (2016). Multimodal Vacuum-Assisted Plasma Ion (VaPI) Source with Transmission Mode and Laser Ablation Sampling Capabilities. Journal of The American Society for Mass Spectrometry, 27 (5), 897-907.
http://dx.doi.org/10.1007/s13361-016-1354-8

Kaddi, C. D., Bennett, R. V., Paine, M. R., Banks, M. D., Weber, A. L., Fernández, F. M., & Wang, M. D. (2015). DetectTLC: Automated Reaction Mixture Screening Utilizing Quantitative Mass Spectrometry Image Features. Journal of The American Society for Mass Spectrometry, 27(2) 359-365.
http://doi.dx.org/10.1007/s13361-015-1293-9
Pasek, M., Herschy, B., & Kee, T. P. (2015). Phosphorus: a Case for Mineral-Organic Reactions in Prebiotic Chemistry. Origins of Life and Evolution of Biospheres, 1-12.
http://dx.doi.org/10.1007/s11084-015-9420-y

Grover, M. A., He, C. Y., Hsieh, M. C., & Yu, S. S. (2015). A Chemical Engineering Perspective on the Origins of Life. Processes, 3(2), 309-338.
http://dx.doi.org/10.3390/pr3020309

Pirim, C., Gann, R. D., McLain, J. L., & Orlando, T. M. (2015). Electron-molecule chemistry and charging processes on organic ices and Titan’s icy aerosol surrogates. Icarus, 258, 109-119.
http://dx.doi.org/10.1016/j.icarus.2015.06.006

Clairmont, R. M., Bommarius, A. S., & Weber, A. L. (2015). Imidazolium Catalysts Formed by an Iterative Synthetic Process as a Model System for Chemical Evolution. Journal of molecular evolution, 81(1-2), 1-9.
http://dx.doi.org/10.1007/s00239-015-9687-7

Forsythe, J. G., Petrov, A. S., Walker, C. A., Allen, S. J., Pellissier, J. S., Bush, M. F., & Fernández, F. M. (2015). Collision cross section calibrants for negative ion mode traveling wave ion mobility-mass spectrometry. Analyst.
http://dx.doi.org/10.1039/C5AN00946D

Diez-Martinez, A., Kim, E. K., & Krishnamurthy, R. (2015). Hydrogen-Bonding Complexes of 5-Azauracil and Uracil Derivatives in Organic Medium. The Journal of organic chemistry, 80(14), 7066-7075.
http://dx.doi.org/10.1021/acs.joc.5b00911

Cafferty, B. J., & Hud, N. V. (2015). Was a Pyrimidine‐Pyrimidine Base Pair the Ancestor of Watson‐Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA. Israel Journal of Chemistry.
http://dx.doi.org/10.1002/ijch.201400206

Smith, J. E., Liang, C., Tseng, M., Li, N., Li, S., Mowles, A. K., & Lynn, D. G. (2015). Defining the Dynamic Conformational Networks of Cross‐β Peptide Assembly. Israel Journal of Chemistry.
http://dx.doi.org/10.1002/ijch.201500012

Gállego, I., Grover, M. A., & Hud, N. V. (2015). Folding and Imaging of DNA Nanostructures in Anhydrous and Hydrated Deep‐Eutectic Solvents. Angewandte Chemie International Edition.
http://dx.doi.org/10.1002/anie.201412354

Forsythe, J. G., Yu, S. S., Mamajanov, I., Grover, M. A., Krishnamurthy, R., Fernández, F. M., & Hud, N. V. (2015). Ester‐Mediated Amide Bond Formation Driven by Wet–Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth. Angewandte Chemie International Edition, 54(34), 9871-9875.
http://dx.doi.org/10.1002/anie.201503792

Pasek, M. A. (2015). Phosphorus as a lunar volatile. <em>Icarus</em>.
http://dx.doi.org/10.1016/j.icarus.2014.07.031

Efthymiou, T. & Krishnamurthy, R. (2015). Microwave-Assisted Phosphitylation of DNA and RNA Nucleosides and Their Analogs. <em>Current Protocols Nucleic Acid Chemistry</em>. 60:2.19.1-2.19.20.
http://dx.doi. 10.1002/0471142700.nc0219s60

Krishnamurthy, R. (2015). On the Emergence of RNA. <em>Israel Journal of Chemistry</em>, 0000(00), 1-15
http://dx.doi.org/10.1002/ijch.201400180

Curtis, M., Keelor, J. D., Jones, C. M., Pittman, J. J., Jones, P. R., Sparkman, O. D., & Fernández, F. M. (2015). Schlieren visualization of fluid dynamics effects in direct analysis in real time mass spectrometry. <em>Rapid Communications in Mass Spectrometry</em>, 29(5), 431-439.
http://dx.doi.org/10.1002/rcm.7119

Basaran, I., Wang, X., Alamgir, A., Wang, J., Haque, S. A., Zhang, Y., Powell, M. R., Leszcynski, J., & Hossain, M. A. (2015). Synthesis and anion binding properties of a urea-based molecular cleft. <em>Tetrahedron Letters</em>, 56(5), 657-661.
http://dx.doi.org/10.1016j.tetlet.2014.12.015

Parker, E. T., Zhou, M., Burton, A. S., Glavin, D. P., Dworkin, J. P., Krishnamurthy, R., Fernández, F. M. & Bada, J. L. (2014). A plausible simultaneous synthesis of amino acids and simple peptides on the primordial Earth. <em>Angewandte Chemie</em>, 126(31), 8270-8274.
http://dx.doi.org/10.1002/ange.201403683

Li, S., Sidorov, A. N., Mehta, A. K., Bisignano, A. J., Das, D., Childers, W. S., Schuler, E., Jiang, Z., Orlando, T.M., Berland, K., & Lynn, D. G. (2014). Neurofibrillar Tangle Surrogates: Histone H1 Binding to Patterned Phosphotyrosine Peptide Nanotubes. <em>Biochemistry</em>, 53(26), 4225-4227.
http://dx.doi.org/10.1021/bi500599a

Krishnamurthy, R. (2014). RNA as an Emergent Entity: An Understanding Gained Through Studying its Nonfunctional Alternatives. <em>Synlett</em>, 25(11), 1511-1517.
http://dx.doi.org/10.1055/s-0033-1340183

Meher, G., Efthymiou, T., Stoop, M., & Krishnamurthy, R. (2014). Microwave-assisted preparation of nucleoside-phosphoramidites. <em>Chemical Communications</em>, 50(56), 7463-7465.
http://dx.doi.org/10.1039/C4CC03092C

Hernandez, A. F., Wagner, M. J., & Grover, M. A. (2014). Model identification of a template-directed peptide network for optimization in a continuous reactor. <em>Chemical Communications</em>, 50(29), 3849-3851.
http://dx.doi.org/10.1039/C4CC00501E

Guo, Q., Mehta, A. K., Grover, M. A., Chen, W., Lynn, D. G., & Chen, Z. (2014). Shape selection and multi-stability in helical ribbons. <em>Applied Physics Letters</em>, 104(21), 211901.
http://dx.doi.org/10.1063/1.4878941

Kim, K., Punna, V., Karri, P., & Krishnamurthy, R. (2014). Synthesis of phosphoramidites of isoGNA, an isomer of glycerol nucleic acid. Beilstein <em>Journal of Organic Chemistry</em>, 10(1), 2131-2138.
http://dx/doi.org/10.3762/bjoc.10.220

Gull, M., Zhou, M., Fernández, F. M., & Pasek, M. A. (2014). Prebiotic phosphate ester syntheses in a deep eutectic solvent. <em>Journal of Molecular Evolution</em>, 78(2), 109-117.
http://dx.doi.org/10.1007/s00239-013-9605-9

Cafferty, B. J., Avirah, R. R., Schuster, G. B., & Hud, N. V. (2014). Ultra-sensitive pH control of supramolecular polymers and hydrogels: pKa matching of biomimetic monomers. <em>Chemical Science</em>, 5(12), 4681-4686.
http://dx.doi.org/10.1039/C4SC02182G

Smith, J. E., Mowles, A. K., Mehta, A. K., & Lynn, D. G. (2014). Looked at Life from Both Sides Now. <em>Life</em>, 4(4), 887-902.
http://dx.doi.org/10.3390/life4040887

Pasek, M. A., Sampson, J. M., & Atlas, Z. (2014). Redox chemistry in the phosphorus biogeochemical cycle. <em>Proceedings of the National Academy of Sciences</em>, 111(43), 15468-15473.
http://dx.doi.org/10.1073/pnas.1408134111

Newton, P. N., Tabernero, P., Dwivedi, P., Culzoni, M. J., Monge, M. E., Swamidoss, I., Green, M.D., Jähnke, R., Santos de Oliviera, S., Simano, J., White, N.J., & Fernández, F. M. (2014). Falsified medicines in Africa: all talk, no action. <em>The Lancet Global Health</em>, 2(9), e509-e510. (Access to CCE instrumentation was acknowledged in this high profile study)
http://dx.doi.org/10.1016/S2214-109X(14)70279-7

Monge, M. E., Dwivedi, P., Zhou, M., Payne, M., Harris, C., House, B., Juggins, Y., Cizmarik, P., Newton, P.N., Fernández, F.M., & Jenkins, D. (2014). A tiered analytical approach for investigating poor quality emergency contraceptives.<em> PloS one </em>, 9(4), e95353. (Access to CCE instrumentation was acknowledged in this high profile study)
http://dx.doi.org/10.1371/journal.pone.0095353 

Reininger, C., Woodfield, K., Keelor, J. D., Kaylor, A., Fernández, F. M., & Farnsworth, P. B. (2014). Absolute number densities of helium metastable atoms determined by atomic absorption spectroscopy in helium plasma-based discharges used as ambient desorption/ionization sources for mass spectrometry. <em> Spectrochimica Acta Part B: Atomic Spectroscopy </em>, 100, 98-104.
http://dx.doi.org/10.1016/j.sab.2014.08.012

Symonds, J. M., Gann, R. N., Fernández, F. M., & Orlando, T. M. (2014). Microplasma Discharge Vacuum Ultraviolet Photoionization Source for Atmospheric Pressure Ionization Mass Spectrometry. <em> Journal of the American Society for Mass Spectrometry </em>, 25(9), 1557-1564.
http://dx.doi.org/10.1007/s13361-014-09375

Keelor, J. D., Dwivedi, P., & Fernández, F. M. (2014). An Effective Approach for Coupling Direct Analysis in Real Time with Atmospheric Pressure Drift Tube Ion Mobility Spectrometry. <em>Journal of the American Society for Mass Spectrometry</em>, 25(9), 1538-1548.
http://dx.doi.org/10.1007/s13361-014-0926-8

Cleaves, H. J., Neish, C., Callahan, M. P., Parker, E., Fernández, F. M., & Dworkin, J. P. (2014). Amino acids generated from hydrated Titan tholins: Comparison with Miller–Urey electric discharge products. <em>Icarus</em>, 237, 182-189.
http://dx.doi.org/10.1016/j.icarus.2014.04.042

Räsänen, R. M., Dwivedi, P., Fernández, F. M., & Kauppila, T. J. (2014). Desorption atmospheric pressure photoionization and direct analysis in real time coupled with travelling wave ion mobility mass spectrometry. <em> Rapid Communications in Mass Spectrometry </em>, 28(21), 2325-2336.
http://dx.doi.org/10.1002/rcm.7028

Cafferty, B. J., & Hud, N. V. (2014). Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology. <em>Current Opinion in Chemical Biology</em>, 22, 146-157.
http://dx.doi.org/10.1016/j.cbpa.2014.09.015

Gull, M. (2014). Prebiotic Phosphorylation Reactions on the Early Earth. <em>Challenges</em>, 5(2), 193-212.
http://dx.doi.org/10.3390/challe5020193

Pirim, C., Pasek, M. A., Sokolov, D. A., Sidorov, A. N., Gann, R. D., & Orlando, T. M. (2014). Investigation of schreibersite and intrinsic oxidation products from Sikhote-Alin, Seymchan, and Odessa meteorites and Fe3P and Fe2NiP synthetic surrogates. <em>Geochimica et Cosmochimica Acta</em>, 140, 259-274.
http://dx.doi.org/10.1016/j.gca.2014.05.027

Hernandez, A. F., Wagner, M. J., & Grover, M. A. (2014). Model identification of a template-directed peptide network for optimization in a continuous reactor. <em>Chemical Communications</em>, 50(29), 3849-3851.
http://dx.doi.org/10.1039/C4CC00501E

Bennett, R. V., Morzan, E. M., Huckaby, J. O., Monge, M. E., Christensen, H. I., & Fernández, F. M. (2014). Robotic plasma probe ionization mass spectrometry (RoPPI-MS) of non-planar surfaces. <em>Analyst</em>, 139(11), 2658-2662.
http://dx.doi.org/10.1039/C4AN00277F

Portella, G., Germann, M. W., Hud, N.V., & Orozco, M. (2014). MD and NMR Analyses of Choline and TMA Binding to Duplex DNA: On the Origins of Aberrant Sequence-Dependent Stability by Alkyl Cations in Aqueous and Water-Free Solvents. <em>Journal of the American Chemical Society</em>, 136(8), 3075-3086.
http://dx.doi.org/10.1021/ja410698u 

Dawley, M. M., Pirim, C. , & Orlando, T. M. (2014). Radiation Processing of Formamide and Formamide: Water Ices on Silicate Grain Analog. <em> The Journal of Physical Chemistry A</em>, 118(7), 1228-1236.
http://dx.doi.org/10.1021/jp4042815 

Dawley, M. M., Pirim, C., & Orlando, T. M. (2014). Thermal Processing of Formamide Ices on Silicate Grain Analogue. <em>The Journal of Physical Chemistry A</em>, 118(7), 1220-1227.
http://dx.doi.org/10.1021/jp404026s 

Mamajanov, I., MacDonald, P. J., Ying, J., Duncanson, D. M., Dowdy, G. R., Walker, C. A., Engelhart, A. E., Fernández, F. M., Grover, M. A., Hud, N. V., & Schork, F. J. (2014). Ester Formation and Hydrolysis during Wet–Dry Cycles: Generation of Far-from-Equilibrium Polymers in a Model Prebiotic Reaction. <em>Macromolecules</em>, 47(4), 1334-1343.
http://dx.doi.org/10.1021/ma402256d 

Parker, E. T., Cleaves, H.J., Burton, A. S., Glavin, D. P., Dworkin, J. P., Zhou, M., Bada, J. L., & Fernández, F. M. (2013). Conducting Miller-Urey Experiments. <em>Journal of Visualized Experiments</em>, 83, 1-13.
http://dx.doi.org/10.3791/51039 

Chen, M.C., Cafferty, B.J., Mamajanov, I., Gallego, I., Khanam, J., Krishnamurthy, R., & Hud, N.V. (2013). Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle. <em>Journal of the American Chemical Society</em>, 136(15), 5640-5646.
http://dx.doi.org/10.1021/ja410124v 

Stoop, M., Meher, G., Karri, P., & Krishnamurthy, R. (2013). Chemical Etiology of Nucleic Acid Structure: The Pentulofuranosyl Oligonucleotide Systems: The (1' -> 3')-beta-L-Ribulo, (4' -> 3')-alpha-L-Xylulo, and (1' -> 3')-alpha-L-Xylulo Nucleic Acids. <em>Chemistry: A European Journal</em>, 19 (45), 15336-15345.
http://dx.doi.org/10.1002/chem.201302219 

Butch, C., Cope, E.D., Pollet, P., Gelbaum, L., Krishnamurthy, R., & Liotta, C.L., (2013). Production of Tartrates by Cyanide-Mediated Dimerization of Glyoxylate: A Potential Abiotic Pathway to the Citric Acid Cycle. <em>Journal of the American Chemical Society</em>, 135 (36), 13440-13445.
http://dx.doi.org/10.1021/ja405103r 

Pasek, M.A., Harnmeijer, J. P., Buick, R., Gull, M., & Atlas, Z. (2013). Evidence for reactive reduced phosphorus species in the early Archean ocean. <em>Proceedings of the National Academy of Sciences USA</em>, 110 (25), 10089-94.
http://dx.doi.org/10.1073/pnas.1303904110 

Karri, P., Punna, V., Kim, K., & Krishnamurthy, R. (2013). Base-pairing properties of isoGNA. <em>Angewandte Chemie, International Edition</em, 52 (22), 5840-5844.
http://dx.doi.org/10.1002/anie.201300795 

Cleaves, H.J. (2013). <em>Prebiotic Chemistry: Geochemical Context and Reaction Screening</em>. Life, 3 (2), 331-345.
http://dx.doi.org/10.3390/life3020331 

Gull, M. & Pasek M. A. (2013). Is Struvite a Prebiotic Mineral? <em>Life</em>, 3(2), 321-330.
http://dx.doi.org/10.3390/life3020321

Wang, J., Gu, J., Nguyen, M. T., Springsteen, G., & Leszczynski, J. (2013). From Formamide to Adenine: A Self-Catalytic Mechanism for an Abiotic Approach. <em>The Journal of Physical Chemistry B</em>, 117(45), 14039-14045.
http://dx.doi.10.1021/jp409296k

Wang, J., Gu, J., Nguyen, M. T., Springsteen, G., & Leszczynski, J. (2013). From Formamide to Purine: A Self-Catalyzed Reaction Pathway Provides a Feasible Mechanism for the Entire Process. <em>The Journal of Physical Chemistry B</em>, 117(32), 9333-9342.
http://dx.doi.10.1021/jp404540x

Hud, N.V., Cafferty, B.J., Krishnamurthy, R., & Williams, L.D. (2013). The Origin of RNA and “My Grandfather’s Axe”. <em>Chemistry & Biology</em>, 20(4), 466-474.
http://dx.doi.org/10.1016/j.chembiol.2013.03.012 

Monge, M. E., Harris, G.A., Dwivedi, P., & Fernández, F.M. (2013). Mass Spectrometry: Recent Advances in Direct Open Air Surface Sampling/Ionization. <em>Chemical Reviews</em>, 113 (4), 2269-2308.
http://dx.doi.org/10.1021/cr300309q 

Cafferty, B.J., Gállego, I., Chen, M.C., Farley, K.I., Eritja R., & Hud, N.V. (2013). Efficient self-assembly in water of long noncovalent polymers by nucleobase analogs. <em>Journal of the American Chemical Society</em>, 135 (7), 2447-2450.

http://dx.doi.org/10.1021/ja312155v 
Wang, J., Gu, J., Nguyen, M.T., Springsteen, G.S., & Leszczynski, J. (2013). From Formamide to Purine: An Energetically Viable Mechanistic Reaction Pathway. <em>Journal of Physical Chemistry B</em>, 117(8), 2314-2320.
http://dx.doi.org/10.1021/jp311423q 

Bennett, R.V., Cleaves, H.J., Davis, J.M., Sokolov, D.A., Orlando, T.M., Bada, J. L., & Fernández, F. M. (2013). Desorption Electrospray Ionization Imaging Mass Spectrometry as a Tool for Investigating Model Prebiotic Reactions on Mineral Surfaces. <em>Analytical Chemistry</em>, 85(3), 1276–1279.
http://dx.doi.org/10.1021/ac303202n 

Bada, J.L. (2013). New insights into prebiotic chemistry from Stanley Miller’s spark discharge experiments. <em>Chemical Society Reviews</em>, 42, 2186-2196.
http://dx.doi.org/10.1039/C3CS35433D 

Kuruvilla, E., Schuster, G. B., & Hud, N. V. (2013). Enhanced Nonenzymatic Ligation of Homopurine Miniduplexes: Support for Greater Base Stacking in a Pre‐RNA World. <em>ChemBioChem</em>, 14(1), 45-48.
http://dx.doi.org/10.1002/cbic.201200601 

Goodwin, J. T., Mehta A. K., & Lynn D. G. (2012). Digital and Analog Chemical Evolution. <em>Account of Chemical Research</em>, 4551(12), 2189–2199.
http://dx.doi.org/10.1021/ar300214w 

Krishnamurthy, R. (2012). Role of pKa of Nucleobases in the Origins of Chemical Evolution. <em>Accounts of Chemical Research</em>, 45(12), 2035-2044.
http://dx.doi.org/10.1021/ar200262x
 
Michalkova S.A., Dawley, M. M., Orlando, T. M., Hill, F. C., & Leszczynski, J. (2012). Theoretical Study of the Roles of Na+ and Water on the Adsorption of Formamide on Kaolinite Surfaces. <em>The Journal of Physical Chemistry C</em>, 116(45), 23992–005.
http://dx.doi.org/10.1021/jp3045324 

Dawley, M. M., Michalkova S.A. Hill, F. C., Leszczynski, J., & Orlando T. M. (2012). Adsorption of Formamide on Kaolinite Surfaces: A Combined Infrared Experimental and Theoretical Study. <em>Journal of Physical Chemistry C</em>, 116(45), 23981-91.
http://dx.doi.org/10.1021/jp304529n 

Cleaves, H. J. (2012). Prebiotic chemistry: What we know, what we don’t. <em>Evolution: Education and Outreach</em>, 5(3), 342-360.
http://dx.doi.org/10.1007/s12052-012-0443-9 

Ni, R., Childers, W. S., Hardcastle, K. I., Mehta, A. K., & Lynn, D. G. (2012). Remodeling Cross-β Nanotube Surfaces with Peptide/Lipid Chimeras. <em>Angewandte Chemie, International Edition</em>, 51, 6635-6638.
http://dx.doi.org/10.1002/anie.201201173 

Lannan, F., Mamajanov, I., & Hud, N.V. (2012). Human Telomere Sequence DNA in Water-Free and High-Viscosity Solvents: G-quadruplex Folding Governed by Kramers Rate Theory, <em>Journal of the American Chemical Society</em>, 134(37), 15324-15330. 
http://dx.doi.org/10.1021/ja303499m 

Childers, W. S., Anthony, N. R., Mehta, A. K., Berland, K. M., & Lynn, D. L. (2012). Phase Networks of Cross-β Peptide Assemblies, <em>Langmuir</em>, 28, 6386-6395.
http://dx.doi.org/10.1002/10.1021/la300143j 

Engelhart, A.E., Cafferty, B.J., Okafor, C.D., Chen, M.C., Williams, L.D., Lynn, D.G., & Hud, N.V. (2012). Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR, <em>ChemBioChem</em>, 13, 1121-1124.
http://dx.doi.org/10.1002/cbic.201200167 

Walker, S.I., Grover, M.A., & Hud, N.V. (2012). Universal Sequence Replication, Reversible Polymerization and Early Functional Biopolymers: A Model for the Initiation of Prebiotic Sequence Evolution, <em>PLoS ONE</em>, 7, e34166.
http://dx.doi.org/10.1371/pone.0034166 

Hudson, J. S., Eberle, J. F., Vachhani, R. H., Rogers, L. C., Wade, J. H., Krishnamurthy, R., & Springsteen, G. (2012).  A unified mechanism for abiotic adenine and purine synthesis in formamide, <em>Angewandte Chemie, International Edition</em>, 51, 5134-5137.
http://dx.doi.org/10.1002/anie.201108907 

Sagi, V. N., Punna, V., Hu, F., Meher, G., & Krishnamurthy, R. (2012). Exploratory experiments on the chemistry of the "glyoxylate scenario": formation of ketosugars from dihydroxyfumarate, <em>Journal of the American Chemical Society</em>, 134, 3577.
http://dx.doi.org/10.1021/ja211383c 

Li, X. Y., Hernandez, A. F., Grover, M. A., Hud, N. V., & Lynn, D. G. (2011). Step-Growth Control in Template-Directed Polymerization, <em>Heterocycles</em>, 82, 1477.
http://dx.doi.org/10.3987/COM-10-S(E)99 

Meher, G. & Krishnamurthy, R. (2011). An expedient synthesis of L-ribulose and derivatives, <em>Carbohydrate Research</em>, 346, 703-707.
http://dx.doi.org/10.1016/j.carres.2011.01.013 

Parker, E. T., Cleaves, H. J., Dworkin, J. P., Glavin, D. P., Callahan, M., Aubrey, A., Lazcano, A., & Bada, J.L. (2011). Primordial synthesis of amines and amino acids in a 1958 Miller H2S-rich spark discharge experiment, <em>Proceedings of the National Academy of Sciences USA</em>, 108, 5526-5531.
http://dx.doi.org/10.1073/pnas.1019191108 

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